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Intrinsic Functional Hypoconnectivity in Core Neurocognitive Networks Suggests Central Nervous System Pathology in Patients with Myalgic Encephalomyelitis: A Pilot Study

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Check out this Knowledge Base article from StressTherapy Solutions: Intrinsic Functional Hypoconnectivity in Core Neurocognitive Networks Suggests Central Nervous System Pathology in Patients with Myalgic Encephalomyelitis: A Pilot Study.

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Study at a glance

Area
QEEG, Methods & Mechanisms
Study type
Controlled study
Authors
Zinn ML, Zinn MA, Jason LA
Journal
Applied Psychophysiology and Biofeedback
Year
2016
Participants
18 (9 patients, 9 controls)
Population
Adults
Protocol
19-channel eLORETA connectivity

Key findings

  • Reduced alpha and alpha-2 activity in posterior regions
  • Hypo-connectivity in the executive, salience and default mode networks

DOI 10.1007/s10484-016-9331-3 → PubMed 26869373 →

A pilot eLORETA study comparing nine patients with myalgic encephalomyelitis (chronic fatigue syndrome) with nine healthy controls. Patients showed reduced alpha activity in posterior regions and weaker connectivity within the central executive, salience and default mode networks, which may underlie their cognitive problems.