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Safety and cognitive effect of frontal DC brain polarization in healthy individuals

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Check out this Knowledge Base article from StressTherapy Solutions: Safety and cognitive effect of frontal DC brain polarization in healthy individuals.

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Study at a glance

Area
QEEG, Methods & Mechanisms
Study type
Randomized controlled trial
Authors
Iyer MB, Mattu U, Grafman J, Lomarev M, Sato S, Wassermann EM
Journal
Neurology
Year
2005
Participants
103 (three experiments)
Population
Adults
Protocol
Anodal, cathodal or sham tDCS, left prefrontal
Sessions
1 (20 minutes)

Key findings

  • Safe and well tolerated
  • 2 mA anodal stimulation improved verbal fluency

DOI 10.1212/01.wnl.0000152986.07469.e9 → PubMed 15753425 →

Healthy adults received 20 minutes of anodal, cathodal or sham direct current over the left prefrontal cortex at 1 or 2 mA, with tests of speed, mood and verbal fluency. Stimulation was well tolerated. At 2 mA, anodal stimulation improved verbal fluency and cathodal slightly reduced it, with no other meaningful effects.