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Human EEG gamma oscillations in neuropsychiatric disorders

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Check out this Knowledge Base article from StressTherapy Solutions: Human EEG gamma oscillations in neuropsychiatric disorders.

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Study at a glance

Area
QEEG, Methods & Mechanisms
Study type
Review & meta-analysis
Authors
Herrmann CS, Demiralp T
Journal
Clinical Neurophysiology
Year
2005
Protocol
review of EEG gamma oscillations

Key findings

  • In schizophrenia, negative symptoms track reduced gamma responses while hallucinations coincide with increased gamma
  • Gamma activity is reduced in Alzheimer's disease
  • Gamma is increased in epilepsy, possibly reflecting cortical excitation and experiences such as déjà vu
  • People with ADHD also show increased gamma amplitudes

DOI 10.1016/j.clinph.2005.07.007 → PubMed 16253555 →

A literature review of how gamma oscillations (fast EEG activity of about 30-80 Hz) change in neuropsychiatric disorders. The authors link these changes to a model in which gamma synchrony binds features of an object and supports matching perception against memory, a process shaped by attention. They propose a 'gamma axis' on which disorders such as schizophrenia, Alzheimer's disease, epilepsy and ADHD can be placed according to reduced or increased gamma activity.