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Standardized low-resolution brain electromagnetic tomography (sLORETA): technical details

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Check out this Knowledge Base article from StressTherapy Solutions: Standardized low-resolution brain electromagnetic tomography (sLORETA): technical details.

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Study at a glance

Area
QEEG, Methods & Mechanisms
Study type
Observational study
Authors
Pascual-Marqui RD
Journal
Methods and Findings in Experimental and Clinical Pharmacology 24 Suppl D:5-12
Year
2002
Protocol
EEG/MEG source localization (sLORETA) mathematics

Key findings

  • sLORETA standardizes the minimum norm current density estimate to infer source location
  • Reported to localize point sources with zero error
  • Per the author, minimum norm misplaces deep sources onto the outer cortex and the Dale et al. method has systematic non-zero error
  • Average reference transforms of the EEG and lead field are used for EEG cases

This paper sets out the mathematical details of standardized low resolution brain electromagnetic tomography (sLORETA), a linear method for imaging electric neuronal activity from EEG or magnetoencephalography (MEG) recordings. It starts from the minimum norm solution but bases localization on standardized current density estimates, and the author reports that this gives zero localization error for point sources, unlike the earlier Dale et al. approach. The stated aim is to let researchers test, reproduce and validate the method.