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Decoding Parkinson’s disease: a systematic review of qEEG biomarkers across clinical domains

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Check out this Knowledge Base article from StressTherapy Solutions: Decoding Parkinson’s disease: a systematic review of qEEG biomarkers across clinical domains.

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Study at a glance

Area
QEEG, Methods & Mechanisms
Study type
Review & meta-analysis
Authors
Makhsous M, Izadpanahi M, Rezayat E
Journal
Clinical Neurophysiology Practice
Year
2026
Participants
89 studies
Population
Adults, Older adults

Key findings

  • Slowed posterior rhythm and more theta tracked cognitive impairment
  • Connectivity measures related to gait and freezing
  • qEEG shifted with dopaminergic drugs and neuromodulation
  • Standardisation needed before clinical use

DOI 10.1016/j.cnp.2026.10.007 → PubMed 42965018 →

This systematic review of 89 studies examined quantitative EEG in Parkinson's disease. EEG slowing was the most consistent marker of cognitive decline, connectivity measures linked to motor problems, and EEG changed with medication and neuromodulation including neurofeedback.