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A Report on Phosphatidylcholine Therapy in a down Syndrome Child

STS Instructor Authored by David Cantor

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Check out this Knowledge Base article from StressTherapy Solutions: A Report on Phosphatidylcholine Therapy in a down Syndrome Child.

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Study at a glance

Area
Learning & Development
Study type
Case study
Authors
Cantor DS, Thatcher RW, Ozand P, Kumin L, Rothschild J
Journal
Psychological Reports
Year
1986
Participants
1
Population
Children
Protocol
phosphatidylcholine supplementation with EEG monitoring
Sessions
7 months of supplementation

Key findings

  • EEG measures normalized during supplementation
  • Some abnormalities came back during a placebo phase
  • Speech, language and motor gains exceeded those of comparable peers
  • Preliminary single-case data from a larger study in progress

A single-case report in which a two-and-a-half-year-old boy with Down syndrome took a phosphatidylcholine supplement for seven months, based on the idea that the cholinergic system is impaired in Down syndrome. His EEG moved toward normal during treatment, with some abnormalities returning during a placebo period. His speech, language and motor skills improved beyond those of peers with Down syndrome in similar programs; the authors stress the data are preliminary.