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Acute Disseminated Encephalomyelitis Following Infectious Mononucleosis

STS Instructor Authored by Robert Turner

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Check out this Knowledge Base article from StressTherapy Solutions: Acute Disseminated Encephalomyelitis Following Infectious Mononucleosis.

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Study at a glance

Area
Other research
Study type
Case study
Authors
Bahadori HR, Williams VC, Turner RP, Rumboldt Z, Reigart JR, Fowler SL, Chavis PS, Maria BL
Journal
Journal of Child Neurology
Year
2007
Participants
1
Population
Adolescents

Key findings

  • Seizures, visual changes and altered mental status began two months after Epstein-Barr infection
  • Brain MRI fitted acute disseminated encephalomyelitis, with no evidence of arteritis
  • Viral testing was consistent with a post-infectious process
  • Symptoms improved with high-dose corticosteroids and intravenous immunoglobulin

DOI 10.1177/0883073807300534 → PubMed 17621505 →

A case report of a 17-year-old girl who developed seizures, episodes of visual disturbance and altered mental state two months after Epstein-Barr virus infection (glandular fever). MRI showed white-matter changes typical of acute disseminated encephalomyelitis, an inflammatory brain condition, concentrated in areas supplied by the posterior cerebral arteries, with no sign of inflamed blood vessels, and blood tests pointed to a post-infectious cause. She improved after high-dose steroids and intravenous immunoglobulin.