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The acute effect of music on interictal epileptiform discharges

STS Instructor Authored by Robert Turner

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Check out this Knowledge Base article from StressTherapy Solutions: The acute effect of music on interictal epileptiform discharges.

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Study at a glance

Area
Epilepsy & Seizures
Study type
Controlled study
Authors
Turner RP
Journal
Epilepsy & Behavior
Year
2004
Participants
4 (2 analysable)
Population
Children
Protocol
passive music listening (Mozart K448 vs control music)

Key findings

  • Four children with rolandic epilepsy were recorded; only two could be analysed
  • Spikes per minute fell by about 34% to 51% during Mozart K448 compared with baseline
  • No such reduction was seen with the control piece
  • Tiny pilot sample; results are preliminary

DOI 10.1016/j.yebeh.2004.07.003 → PubMed 15380117 →

A very small randomised, single-blind, crossover pilot trial testing whether listening to Mozart's Sonata for Two Pianos (K448) reduces epileptiform spikes in the EEG of children with benign rolandic epilepsy. Four children had four-hour awake EEG recordings, and spike rates were compared across baseline, the Mozart piece and a control piece (Beethoven's Für Elise). Only two children had enough waking spikes to analyse; in them, spike rates fell by roughly a third to a half during the Mozart piece but not during the control music.