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Escaping the Negative Attentional Bias in Depression with Real-Time Neurofeedback

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Check out this Knowledge Base article from StressTherapy Solutions: Escaping the Negative Attentional Bias in Depression with Real-Time Neurofeedback.

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Study at a glance

Area
Depression & Mood
Study type
Randomized controlled trial
Authors
Lubianiker N, Woods B, Nitchie F, Batzdorf A, Mennen A, Lin Q, Norman KA, Turk-Browne NB, Sheline YI
Journal
MedRxiv
Year
2026
Participants
48 (24 real, 24 sham)
Population
Adults
Protocol
Real-time fMRI attention-decoding neurofeedback
Sessions
3 sessions
Equipment
fMRI

Key findings

  • Real feedback reduced getting stuck in the most negative attentional state versus sham
  • Training reduced activity in precuneus/posterior cingulate and medial prefrontal cortex

DOI 10.64898/2026.09.30.26363896 → PubMed 42926816 →

Forty-eight adults with major depression were randomised to real or sham fMRI neurofeedback designed to help them disengage from negative faces. The real feedback group became less likely to get stuck attending to negative images. This is a preprint and has not been peer reviewed.