Skip to content
Get in touch

Research › ADHD & Attention

Adolescent impulsivity phenotypes characterized by distinct brain networks

Share

Suggested message

Check out this Knowledge Base article from StressTherapy Solutions: Adolescent impulsivity phenotypes characterized by distinct brain networks.

Facebook LinkedIn Email

Facebook doesn't let websites fill in your post. Use Copy message, then paste it in.

Study at a glance

Area
ADHD & Attention
Study type
Observational study
Authors
Whelan R, Conrod PJ, Poline JB, Lourdusamy A, Banaschewski T et al.
Journal
Nature Neuroscience
Year
2012
Participants
1,896
Population
Adolescents
Protocol
fMRI during a stop-signal task

Key findings

  • Distinct cortical and subcortical networks underlie successful and failed inhibition
  • Reduced activity in an orbitofrontal network was linked to starting drug use early
  • Separate networks were associated with ADHD symptoms and with stopping speed

DOI 10.1038/nn.3092 → PubMed 22544311 →

A very large brain-imaging study of 14-year-olds from the European IMAGEN project, mapping the brain networks behind successful and failed attempts to stop an action. Impulsivity turned out not to be one thing: separate networks were tied to early drug use, to ADHD symptoms and to the speed of stopping, and one was linked to a variant in a noradrenaline transporter gene.