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Alpha power, alpha asymmetry and anterior cingulate cortex activity in depressed males and females

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Check out this Knowledge Base article from StressTherapy Solutions: Alpha power, alpha asymmetry and anterior cingulate cortex activity in depressed males and females.

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Study at a glance

Area
Depression & Mood
Study type
Observational study
Authors
Jaworska N, Blier P, Fusee W, Knott V
Journal
Journal of Psychiatric Research
Year
2012
Participants
96 (53 depressed, 43 controls)
Population
Adults
Protocol
Resting EEG alpha power and asymmetry; sLORETA theta in the anterior cingulate

Key findings

  • 53 unmedicated adults with major depression and 43 controls
  • More frontal and parietal alpha power, and less left mid-frontal activity, in depression
  • Higher theta in the subgenual anterior cingulate (sLORETA)
  • Some patterns differed between depressed men and women

DOI 10.1016/j.jpsychires.2012.08.003 → PubMed 22939462 →

Compared resting EEG in 53 unmedicated adults with major depression and 43 healthy controls. The depressed group, especially the men, showed more frontal and parietal alpha power, a sign of lower cortical activity, and relatively less left mid-frontal activity, and sLORETA found more theta in the subgenual anterior cingulate. Depressed women showed more right parietal activity. The findings support frontal alpha asymmetry and cingulate theta as EEG markers of depression, with some differences between men and women.