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Amygdala Volume Changes in Posttraumatic Stress Disorder in a Large Case-Controlled Veterans Group

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Check out this Knowledge Base article from StressTherapy Solutions: Amygdala Volume Changes in Posttraumatic Stress Disorder in a Large Case-Controlled Veterans Group.

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Study at a glance

Area
PTSD & Trauma
Study type
Controlled study
Authors
Morey RA, Gold AL, LaBar KS, Beall SK, Brown VM, Haswell CC, Nasser JD, Wagner HR, McCarthy G, Mid-Atlantic MIRECC Workgroup
Journal
Archives of General Psychiatry
Year
2012
Participants
200 (99 PTSD, 101 controls)
Population
Adults

Key findings

  • Smaller amygdala volume in PTSD
  • Analysis controlled for alcohol, depression and medication

DOI 10.1001/archgenpsychiatry.2012.50 → PubMed 23117638 →

A large study of recent military veterans comparing MRI brain volumes in those with and without PTSD, all trauma-exposed. Smaller amygdala volume was associated with PTSD after accounting for depression, alcohol use and medication.