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Functional Connectivity and Aging: Comodulation and Coherence Differences

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Check out this Knowledge Base article from StressTherapy Solutions: Functional Connectivity and Aging: Comodulation and Coherence Differences.

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Study at a glance

Area
QEEG, Methods & Mechanisms
Study type
Observational study
Authors
Kaiser DA
Journal
Journal of Neurotherapy
Year
2008
Participants
101 (ages 5-35; 34 female, 67 male)
Population
Children, Adolescents, Adults
Protocol
resting EEG coherence and comodulation

Key findings

  • Coherence and comodulation increased with age below 30 Hz at most sites
  • Anterior connectivity changed with age in adults but not in children
  • The strongest age effect was alpha comodulation at site T5
  • Proposes a 'Periodicity Table' framework for EEG synchrony measures

This study compared two measures of how EEG signals at different sites relate: coherence (synchrony of timing, or phase) and comodulation (synchrony of strength, or magnitude). Eyes-closed resting EEG from 101 people aged 5 to 35 was analyzed across 10 frequency bands. Connectivity rose steadily with age, and frontal connectivity grew in adulthood but not childhood. The author suggests EEG connectivity may partly reflect patterns of myelination, and proposes a framework for organizing such measures.