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Mapping the Structural Core of Human Cerebral Cortex

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Check out this Knowledge Base article from StressTherapy Solutions: Mapping the Structural Core of Human Cerebral Cortex.

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Study at a glance

Area
QEEG, Methods & Mechanisms
Study type
Observational study
Authors
Hagmann P, Cammoun L, Gigandet X, Meuli R, Honey CJ, Wedeen VJ, Sporns O
Journal
PLoS Biology
Year
2008
Participants
5 participants
Protocol
diffusion spectrum imaging and resting-state fMRI

Key findings

  • A structural core was found in posterior medial and parietal cortex
  • Core regions act as connector hubs linking all major structural modules
  • The core includes the posterior parts of the brain's default network
  • Structural connectivity corresponded substantially with resting-state functional connectivity

DOI 10.1371/journal.pbio.0060159 → PubMed 18597554 →

A brain imaging study that mapped the long-range nerve fiber connections of the human cortex using diffusion spectrum imaging, a form of MRI. Network analysis revealed a highly connected "structural core" in the posterior medial and parietal cortex, linked to several distinct frontal and temporal modules. Structural connections closely matched resting-state functional connectivity in the same people. The authors conclude that the core's central position suggests an important role in integrating brain function.