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The slow and infraslow oscillations of cortical neural network

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Check out this Knowledge Base article from StressTherapy Solutions: The slow and infraslow oscillations of cortical neural network.

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Study at a glance

Area
QEEG, Methods & Mechanisms
Study type
Observational study
Authors
Keković G, Sekulić S, Podgorac J, Mihaljev-Martinov J, Gebauer-Bukurov K
Journal
Neurology, Psychiatry and Brain Research
Year
2012
Participants
23 patients with epileptic seizures, 23 healthy volunteers
Protocol
EEG spectral power and coherence of infraslow and delta activity

Key findings

  • Both generalized and focal seizures showed a characteristic spectral peak around 1.5 Hz
  • A slow 0.05 Hz rhythm (period of about 20 s) was pronounced in generalized but not focal seizures
  • In healthy volunteers, spectral coherence between brain regions was significantly modulated by ISOs
  • Authors suggest ISOs play a role in normal brain functioning, not only in seizures

DOI 10.1016/j.npbr.2012.04.003 →

This study examined very slow EEG rhythms, infraslow oscillations (ISOs, around 0.05 Hz) and the delta band, in patients during generalized or focal epileptic seizures and in healthy volunteers performing real and imagined hand and foot movements. Spectral power and coherence between frontal and parietal signals were compared across groups. Both seizure types showed a spectral peak near 1.5 Hz, with a 0.05 Hz rhythm prominent in generalized seizures. The authors conclude that ISOs also modulate coordination between brain regions in healthy people, so their role may extend beyond epilepsy.