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Transcranial direct current stimulation for the outpatient treatment of poor-responder depressed patients

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Check out this Knowledge Base article from StressTherapy Solutions: Transcranial direct current stimulation for the outpatient treatment of poor-responder depressed patients.

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Study at a glance

Area
Depression & Mood
Study type
Pilot / open study
Authors
Dell'Osso B, Zanoni S, Ferrucci R, Vergari M, Castellano F, D'Urso N, et al.
Journal
European Psychiatry
Year
2012
Participants
23
Population
Adults
Protocol
tDCS added to medication
Sessions
10 over 5 days

Key findings

  • Response rose from 17% at the end of treatment to 30% a week later
  • Well tolerated

DOI 10.1016/j.eurpsy.2011.02.008 → PubMed 21621982 →

Twenty-three people with major depression or bipolar depression who had responded poorly to medication received tDCS twice a day for five days in addition to their drugs, with a blinded rater. Depression scores fell significantly by the end of treatment and kept improving over the following week, with no notable side effects.