Knowledge Base: Research

Neurofeedback: A Promising Treatment for Depression

Here’s good news for people struggling with depression. People with depression who are taught a neurofeedback technique that allows them to activate parts of the brain involved in generating positive emotions may be able to lower their depressive symptoms. In a recent study published in PLos ONE (Volume 7, page e38115), researchers instructed 16 people [...]

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Altered Functional Brain Connectivity in a Non-Clinical Sample of Young Adults with Attention-Deficit/Hyperactivity Disorder

by Cocchi et al Abstract Attention-deficit/hyperactivity disorder (ADHD) is characterized by symptoms of inattention and hyperactivity/impulsivity that often persist in adulthood. There is a growing consensus that ADHD is associated with abnormal function of diffuse brain networks, but such alterations remain poorly characterized. Using resting-state functional magnetic resonance imaging, we characterized multivariate (complex network measures), bivariate (network-based statistic), and univariate (regional [...]

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Thalamic shape and connectivity abnormalities in children with attention deficit/hyperactivity disorder

by Xia et al Abstract Attention-deficit/hyperactivity disorder (ADHD) is characterized by widespread structural and functional abnormalities in the cortico-striato-thalmo-cortical (CSTC) loops that subserve attention and executive functions. In this study, we analyzed thalamic shape and its white matter connections using structural MRI and diffusion tensor imaging (DTI) data acquired from children with ADHD (n=19) and [...]

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A QEEG index of level of functional dependence for people sustaining acquired brain injury: the Seville Independence Index (SINDI)

Leon-Carrion J, Martin-Rodriguez JF, Damas-Lopez J, Martin JM, Dominguez-Morales Mdel R. Source Human Neuropsychology Laboratory, School of Psychology, Department of Experimental Psychology, University of Seville, Seville, Spain. leoncarrion@us.es Abstract PRIMARY OBJECTIVE: To find an easy-to-use, valid and reliable tool for evaluating the level of functional dependence of an individual with brain damage who seeks a [...]

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Diagnostic approach to children with minor traumatic brain injury

Wien Med Wochenschr. 2012 Sep;162(17-18):394-399. Epub 2012 Jul 14.Diagnostic approach to children with minor traumatic brain injury. Oster I, Shamdeen GM, Ziegler K, Eymann R, Gortner L, Meyer S. Source Section Neuropediatrics, University Children’s Hospital of Saarland, Homburg, Germany. Abstract: STUDY PURPOSE:To analyse the management of minor traumatic brain injury (MTBI) in paediatric hospitals in [...]

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Use of normative databases and statistical methods in demonstrating clinical utility of QEEG: importance and cautions.

Use of normative databases and statistical methods in demonstrating clinical utility of QEEG: importance and cautions.

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Anatomical connectivity and the resting state activity of large cortical networks

by Pinotsis et al Abstract This paper uses mathematical modelling and simulations to explore the dynamics that emerge in large scale cortical networks, with a particular focus on the topological properties of the structural connectivity and its relationship to functional connectivity. We exploit realistic anatomical connectivity matrices (from diffusion spectrum imaging) and investigate their capacity [...]

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Cognitive reserve impacts on inter-individual variability in resting-state cerebral metabolism in normal aging

by  Christine Bastina et al Abstract There is a great deal of heterogeneity in the impact of aging on cognition and cerebral functioning. One potential factor contributing to individual differences among the elderly is the cognitive reserve, which designates the partial protection from the deleterious effects of aging that lifetime experience provides. Neuroimaging studies examining [...]

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Studying the topological organization of the cerebral blood flow fluctuations in resting state

by Melie-Garsia et al Abstract In this paper the cerebral blood flow (CBF) in resting state obtained from SPECT imaging is employed as a hemodynamics descriptor to study the concurrent changes between brain structures and to build binarized connectivity graphs. The statistical similarity in CBF between pairs of regions was measured by computing the Pearson [...]

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Tracking EEG changes in response to alpha and beta binaural beats

by Vernon et al Abstract A binaural beat can be produced by presenting two tones of differing frequency, one to each ear. Such auditory stimulation has been suggested to influence behaviour and cognition via the process of cortical entrainment. However, research so far has only shown frequency following responses in the traditional EEG frequency ranges [...]

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